Home > Does standing up all day cause varicose veins? > Does standing up all day cause varicose veins? Does standing up all day cause varicose veins? Home > Does standing up all day cause varicose veins? > Does standing up all day cause varicose veins? Although standing for long periods can exacerbate symptoms from varicose veins, it does not cause them. They are caused by your genes. Unfortunately, there is nothing you can do to prevent them from forming if you have the genes.